If you are one of the Millions of Americans dealing with being overweight(BMI of 25-30), obese (BMI of >30), you may be excited about the new weight loss medication that just came on the market in October 2014 called Contrave.
The U.S. FDA approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight management in addition to a reduced-calorie diet and physical activity for those with a body mass index (BMI) of 30 or greater (obesity) or adults with a BMI of 27 or greater (overweight) who have at least one weight-related condition such as high blood pressure (hypertension), type 2 diabetes, or high cholesterol (dyslipidemia).
Obesity leads over 50 different medical problems including high blood pressure, high cholesterol, sleep apnea, diabetes, cardiovascular disease and even increased risk of most cancers(Yes, cancer risk for most Genitourinary and Gastrointestinal cancers goes up with obesity), and it continues to be a major public health problem around the world!
What is contrave for weight loss?
Similar to the other new combination weight loss medication, combination of two FDA-approved drugs, naltrexone and bupropion, is a combination of two medications in an extended-release formulation. While Naltrexone is approved to treat alcohol and opioid dependence. Bupropion is approved to treat depression and seasonal affective disorder and as an aid to smoking cessation treatment.
How effective is Contrave for weight loss?
The clinical effectiveness of Contrave was evaluated in multiple clinical trials that included approximately 4,500 obese and overweight patients with and without significant weight-related conditions treated for one year. All patients received lifestyle modification that consisted of a reduced- calorie diet and regular physical activity.
Results from a many clinical trial that enrolled patients without diabetes showed that patients had an average weight loss of 4.1 percent over treatment with placebo (inactive pill) at one year. In this trial, 42 percent of patients treated with Contrave lost at least 5 percent of their body weight compared with 17 percent of patients treated with placebo.
Side Effects of Contrave
The most common adverse reactions reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.
Does contrave work for me to lose weight?
In order to determine if Contrave or any other weight loss medication is right for you, you would need to schedule a consultation with a physician familiar with this and other weight loss medications such as the W8MD obesity medicine physicians.
Locations where Contrave is offered when appropriate to patients!
Philadelphia Insurance Weight Loss & Sleep Center: 1718, Welsh Rd, Philadelphia, PA, 19115 Ph: 1-215-676-2334
King Of Prussia Weight Loss & Sleep Center: 987 Old Eagle School Rd, Ste 712, Wayne, PA, 19087 Ph: 215-676-2334
NYC Insurance Weight Loss & Sleep Center: 2632 E 21st Street Brooklyn New York 11235 Ph: 1-718-946-5500.